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Understanding the Importance of Imaging in Patient Selection
When treating patients with Geographic Atrophy (GA), one might overlook a crucial factor—the evaluation of Optical Coherence Tomography (OCT) and previous imaging history. Dr. Robert L. Avery highlighted its importance at the recent Retina 2025 conference held in Koloa, Hawaii. He underscored how a careful assessment of the ellipsoid zone (EZ) can inform decisions on patient treatment, aiding practitioners in determining who is most likely to benefit from FDA-approved GA drugs.
Evaluating Fellow Eye Status: A Key Factor
Dr. Avery pointed out that understanding the patient's fellow eye status is essential when considering treatment options. Many choices can exert a significant influence on the treatment's effectiveness and safety. The fellow eye's health and conditions can provide valuable insights into the overall state of the patient's ocular health, which can be paramount in personalized medicine.
The Role of Uveitis and Patient History
A history of uveitis adds another layer of complexity. For patients with this history, practitioners must carefully weigh the risks and potential treatment burdens before proceeding. Dr. Avery suggested that uveitis could complicate the condition, hence, utilizing it as a selection factor helps refine the candidate pool for GA therapeutics.
Identifying Risks to Enhance Patient Care
Using the double-layer sign on OCT images as a risk indicator, Dr. Avery cautioned against treating patients displaying this marker. The potential for developing complications, such as choroidal neovascularization, can interfere significantly with the treatment experience. Here, the takeaway is clear: control your treatment options by understanding the patient's condition, location, and size of GA lesions.
Preservation of the Ellipsoid Zone: An Endpoint for Future Growth
Dr. Avery also explained that the integrity of the EZ serves as more than just an indicator; it acts as a focal point for future GA growth predictions. Practitioners should strive to preserve this zone during treatments as it represents a critical endpoint in managing dry Age-related Macular Degeneration (AMD). This preservation not only fosters positive treatment outcomes but also contributes to long-term patient wellness.
Actionable Insights for Practice Owners
For concierge medical practice owners, staying ahead in the realm of ocular health requires understanding and implementing these insights into practice. By evaluating OCT effectively and considering patient histories meticulously, practitioners can enhance their treatment offerings and foster deeper connections with their patients. This is crucial in establishing a reputation as the top local practice.
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