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June 05.2025
3 Minutes Read

Could the New Blood-Based Epigenetic Clock Transform Aging Approaches?

Could the New Blood-Based Epigenetic Clock Transform Aging Approaches?


Revolutionizing Aging: What is the IC Clock?

A groundbreaking advancement in the realm of gerontology, the newly introduced IC Clock is designed not merely to tell how long a person has lived but to assess the quality of their aging process. This revolutionary blood-based epigenetic clock focuses specifically on intrinsic capacity (IC)—a concept recognized by the World Health Organization (WHO) for its importance in evaluating health as we age. Unlike traditional models that only consider chronological age, the IC Clock evaluates six key functions: mobility, cognition, mental health, vision, hearing, and nutritional vitality.

The Significance of Intrinsic Capacity in Healthcare

Understanding intrinsic capacity offers immense value, especially for concierge health practitioners who cater to an aging clientele. Dr. David Furman, a leading researcher in this innovation, emphasizes the need to shift the focus of medical care. Instead of targeting a disease-free state, health providers should aim for maintaining function. This practical perspective aligns well with the ethos of concierge medicine, which prioritizes personalized care and remains forward-thinking in adopting new medical technologies.

How the IC Clock Works and Its Development

Developed through collaboration across continents by teams at the Buck Institute, IHU HealthAge, and French universities, the IC Clock leverages data from a significant cohort study involving participants aged 20 to 102. The research utilized longitudinal data, incorporating diverse biospecimens—blood, urine, and saliva, which are collected annually. With precision, the IC Clock employs DNA methylation analysis to evaluate patients' intrinsic capacity non-invasively. This streamlined process can bring a large-scale, highly beneficial tool to low- and middle-income countries, ensuring access to efficient age assessment without extensive clinical visits.

Performance and Predictive Capabilities of the IC Clock

One of the IC Clock's standout features is its predictive power regarding overall mortality, outperforming earlier aging clocks. The model correlates higher IC scores with positive immune system responses and healthy lifestyle choices, indicating its potential utility in evaluating the efficacy of longevity-promoting strategies. This represents a significant leap forward, integrating health metrics directly linked to biological aging rather than chronological limits.

The Future of Aging Assessment: Practical Applications

As the healthcare landscape evolves, the demand for customizable, accessible health metrics grows. The implementation of the IC Clock could enable concierge health practitioners to tailor care plans based on individual aging processes. This proficiency allows for early interventions that promote healthy aging, enhancing the quality of life for older patients. With further research and refinement, the clock could seamlessly fit into routine health assessments, further supporting preventative measures tailored to the unique aging profile of each patient.

Cultural Implications for Aging in the Future

As societies become more accustomed to living longer, the implications of aging—both social and economic—will become even more pressing. Implementing tools like the IC Clock across healthcare practices supports a broader understanding that aging is not merely about adding years to life but enhancing the life in those years. For healthcare practitioners, appreciating the nuances of aging that the IC Clock reveals cultivates a more empathetic approach to patient care.

Next Steps for Practitioners

As technology continues to push the boundaries of healthcare, practitioners are called to stay informed about innovations like the IC Clock. Executives should consider integrating emerging technologies that focus on individual patient care, potentially reshaping their practice models to embrace this data-oriented approach to aging. Building partnerships and staying abreast of research developments will ensure that practitioners remain at the forefront of age-related healthcare.

If you’re a concierge health practitioner aiming for excellence in patient care, understanding and implementing tools like the IC Clock will be essential for providing proactive, personalized services to your aging patients.


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06.08.2025

Canid's $10M Funding Revolutionizes Pediatric Vaccine Management for Growing Practices

Update Understanding the Financial Strain in Pediatric PracticesPediatric practices are experiencing escalating financial pressures, with vaccination programs becoming a primary source of strain. Despite their critical importance, many pediatricians find themselves either breaking even or operating at a loss. A staggering 69% of these practices face challenges due to insurance reimbursements and complex inventory management. This financial burden is compounded by increasing administrative tasks, necessitating an innovative approach to vaccine management.Canid's Innovative Solution for Pediatric Vaccine ManagementCanid, founded in 2021, has positioned itself as a game-changer in this landscape. By securing $10 million in Series A funding, the company aims to relieve the overwhelming administrative and financial burden on independent pediatricians. The company focuses on streamlining vaccine management, which often represents the second-largest expense for these practices, only coming behind staff salaries. With over 150 pediatricians already utilizing its platform, Canid has facilitated vaccinations for 121,000 patients across twelve states, demonstrating a robust early success in its mission.Why Automation is Key to Reducing BurnoutOne of the significant issues faced by pediatricians is burnout, exacerbated by the administrative tasks tethered to patient care. Currently, pediatricians spend an average of 15 hours per week managing non-clinical activities. Canid seeks to alleviate this burden through its automated platform that integrates seamlessly with electronic health records (EHR). By scanning a vaccine barcode, pediatricians can offload their administrative tasks—ranging from ordering and billing to compliance with public health standards.Empowering Pediatricians with Data-Driven InsightsThrough data-driven patient outreach, Canid equips practitioners with insights into their patient panels, enhancing vaccination completion rates. The platform leverages AI and automation to track undervaccinated children, thereby addressing public health challenges effectively. As Canid CEO Pedro Sánchez de Lozada states, "Pediatricians spend years training to provide exceptional care for children, not to become experts in revenue cycle management or inventory systems." This philosophy underlines Canid’s goal: to let pediatricians concentrate on their core mission of caring for children.The Future of Pediatric Care: A Vital ShiftAs the healthcare landscape shifts toward consolidation, independent pediatric practices must adopt innovative solutions to thrive amid challenges. Canid’s significant investment paves the way for pediatricians to regain control over their financial health and operational efficiency. In the coming years, as more practices adopt such technologies, we could witness a revitalization of independent pediatric care in America, potentially leading to better health outcomes for children and families.Actionable Steps for Practice GrowthFor independent pediatric practitioners looking to enhance their operations, embracing technology like Canid's platform is not just beneficial—it is essential. Consider conducting a thorough assessment of your practice's current vaccine management strategies and identifying areas that could benefit from automation. Engaging with platforms that offer streamlined administrative solutions can significantly increase efficiency, reduce burnout, and ultimately lead to better patient care.Conclusion: The Importance of Tech in Pediatric PracticesThe significance of Canid’s platform in the realm of pediatric care cannot be understated. By addressing the financial and administrative challenges faced by independent practices, Canid presents a transformative opportunity for pediatricians. As technology continues to evolve, embracing these innovations will not only support practice sustainability but also enhance the quality of care delivered to young patients.

06.08.2025

Omada Health's NASDAQ Debut: A Game Changer for Digital Health Investors

Update Understanding Omada Health's Success: A Strategic Overview Omada Health's recent debut on NASDAQ illustrates a crucial turning point in the digital health landscape, bolstering investor confidence after a wavering market for IPOs. Busting through the initial offering price of $19 to a robust $23 per share, the company signifies a resurgence in investor appetite for digital health entities—especially those that demonstrate scale, revenue growth, and innovative strategies amid ongoing healthcare challenges. Solving Chronic Disease: An Emerging Need With chronic diseases consuming an astonishing $526 billion annually in the U.S., Omada Health's specific focus on addressing these conditions has broad ramifications. Their virtual-first model serves over a million lifetime members and 2,000 enterprise customers, aiming to significantly mitigate the repercussions of obesity, diabetes, and cardiovascular issues. This direct engagement positions them uniquely in a market plagued by traditional healthcare delivery hurdles, and it aligns well with the demand for cost-effective solutions. Innovative Approaches: GLP-1 Strategy Unlike many competitors focused solely on prescribing GLP-1 weight-loss drugs, Omada has established a unique path by integrating behavior change programs tailored for patients using these medications. This comprehensive approach works alongside conventional prescriptions, equipping patients with personalized support in lifestyle management, nutrition, and adherence strategies. Such innovation not only enhances the patient experience but also appeals to major payers and pharmacy benefit managers, adding a substantial layer of financial viability to their model. Leveraging AI for Personalized Care In an era where technology shapes healthcare delivery, Omada Health is successfully incorporating artificial intelligence into its services. Their recent launch of an AI-driven tool for nutritional tracking, ‘OmadaSpark’, exemplifies this dedication. Members receive immediate guidance and support, enhancing user engagement and fostering adherence to healthier lifestyles. This intelligent design underscores how tech integration can lead to better health outcomes, a prospect that provides peace of mind to both patients and health practitioners. The Financial Landscape: Significance of Growth As Omada's revenue ascended by an impressive 57% in the first quarter of 2025, reaching $55 million, it clarified the company’s forward momentum. Incremental financial discipline alongside growth—evidenced by significantly reduced net losses—demonstrates a clear pathway to profitability, a crucial factor attracting investors back into the sector. Such financial health positions Omada to lead initiatives compelling for concierge health practitioners navigating their own growth challenges. The Broader Implications for the Digital Health Sector Omada’s IPO should be viewed as a bellwether for a wider recovery in digital health. Following a quiet phase for public exits, the successful launches of Omada and Hinge Health signal that investor confidence is returning to a market eager for scalable solutions addressing urgent healthcare needs. This is an essential signal for practitioners seeking avenues to integrate technology within their practices while remaining committed to patient-centric care. What This Means for You: Embracing Change As new technologies emerge and the healthcare landscape evolves, staying updated with trends like those seen with Omada's trajectory is vital for concierge health practitioners. Integrating technology can provide streamlined efficiencies, better patient engagement, and enhanced care delivery—critical elements for sustaining a competitive edge in the community. Understanding how to leverage these changes can ease feelings of being overwhelmed by the tech side of your practice. Conclusion: Future Outlook in Digital Health The successful IPO of Omada serves not just as a marker of its own triumph, but as a trajectory for the future of digital health. As practitioners, refining strategies for technology integration now becomes paramount. The signs are clear: understanding and leveraging these market dynamics can support practice growth and optimize patient connections. With healthcare's trajectory towards virtual-first care solidifying, the opportunity for a harmonious blend of technology and patient engagement stands ripe for the taking. Engaging with these innovations can mean profound improvements in practice management and patient satisfaction.

06.08.2025

D-Sorbitol: The Sweet Solution Transforming Medical Hydrogels and Implants

Update The Sweet Revolution in Medical Hydrogels Imagine a future where treating chronic illnesses becomes less about swallowing pills and more about integrating soft, flexible electronic implants into our bodies. This potential reality is closer than we think, thanks to recent advancements in medical technology and a surprisingly sweet ingredient. Recent research led by Dr. Limei Tian at Texas A&M University has uncovered the potential of using D-sorbitol—a safe sugar alternative found in chewing gum—to replace toxic additives traditionally used in conductive hydrogels. These materials are crucial for the function of electronic implants, which are increasingly utilized to diagnose and treat a variety of diseases. What Are Conductive Hydrogels? Conductive hydrogels are soft materials that can mimic the mechanical properties of human tissues. They are designed to enhance the performance of electronic implants, improving their electrical conductivity and flexibility. Current bioelectronic devices have several limitations, primarily due to the use of harmful additives that can lead to negative side effects for patients. Hydrogels made from D-sorbitol provide a promising alternative that is both biocompatible and effective. How D-Sorbitol Enhances Implant Efficiency D-sorbitol not only enhances the hydrogels' electrical properties but also offers greater comfort and compatibility with the body's natural tissues. Dr. Tian noted, "These devices could revolutionize treatments for neurological disorders, paralysis, and chronic pain, making long-term implants more viable and effective." The flexibility of D-sorbitol-based hydrogels means they can adapt to bodily movement, reducing the risk of immune rejection and improving patient outcomes. Potential Applications of Enhanced Hydrogels The applications for these innovative hydrogels extend far beyond neurological devices. They hold promise for: Brain Implants: For disorders such as Parkinson's disease or epilepsy, where precision is key. Nerve Interfaces: To restore movement in patients with spinal cord injuries, bridging the gap between technology and biological function. Wearable Biosensors: For continuous health monitoring, providing real-time feedback about a patient’s well-being. Electronic Skin: Enhancing prosthetics with increased sensory feedback, making them feel more “natural” to the user. Soft Robotics: Incorporating touch sensitivity, which is vital for creating adaptive robotic systems. The Road Ahead: Potential and Challenges While the possibilities are exciting, challenges remain. Creating a conductive hydrogel that maintains biocompatibility over time is crucial. Many current implants trigger immune responses leading to tissue scarring. By leveraging the biocompatible properties of D-sorbitol, researchers aim to mitigate these adverse effects, transforming how we approach implantable electronics. Best Practices for Health Practitioners As this technology advances, health practitioners should consider: Staying informed about new materials and additives that could enhance patient care. Examining existing implant technologies for potential upgrades that could improve patient safety and comfort. Discussing with patients the latest treatment options that may arise from these technological advancements. Overall, it’s clear that D-sorbitol could herald a new era in medical treatments, one where the intersection of technology and biology improves patient outcomes and enhances the quality of life. Conclusion: The Sweet Potential of Hydrogels The successful integration of D-sorbitol in conductive hydrogels represents a significant step towards safer, more effective medical implants. If you’re a healthcare provider, keep an eye on these developments, as they could reshape the treatment options available to your patients.

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R","city":"Sheridan","state":"WY","zip":"82801","email":"info@banidadigital.com","tos":"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","privacy":"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